Somatostatin
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Somatostatin is a growth hormone-inhibiting hormone. Somatostatin is used in the treatment of acromegaly due to hormone secreting tumors.
Indications
Somatostatin is primarily indicated in conditions like Acromegaly and Adjunct in ganciclovir treatment, Esophageal varices bleeding.
Contraindications
Somatostatin is contraindicated in conditions like Pregnancy, Lactation, Hypersensitivity to any component of product.
Side Effects
The severe or irreversible adverse effects of Somatostatin, which give rise to further complications include Thrombocytopenia, Extra systoles. The signs and symptoms that are produced after the acute overdosage of Somatostatin include Transient bradycardia, Cramping. The symptomatic adverse reactions produced by Somatostatin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea and vomiting, Pyrexia, Hypoglycemia, Hypocalcemia.
Warnings
Blood sugar should be monitored since somatotropin may interfere with carbohydrate metabolism. Concomitant parental nutrition has been suggested because of the inhibitory effect on intestinal absorption.
High Risk Groups
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
3 ug/ kg/hr (3 (3)) 12 hourly IV Inf —
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
Somatostatin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementHexobarbitone (Na)Somatostatin has been demonstrated to prolong or enhance the effects of Hexobarbitone (Na).InsulinThe glucoregulatory properties of somatostatin may cause it to interfere with the insulin requirements of insulin-dependent diabeticsTechnetium Tc-99m DisofeninSomatostatin may decrease gallbladder emptying thus delaying gallbladder clearance of technetium Tc 99m disofenin.Technetium Tc-99m lidofeninSomatostatin may decrease gallbladder emptying, thus delaying gallbladder clearance of technetium Tc 99m lidofenin. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
IV Inf Store in a well closed container. Refrigeration is recommended. Protect from Sunlight.
Available Brands in Pakistan
No active brands are currently recorded for this generic.
2 records are present but flagged "Unverified / Legacy" and excluded.