Sparfloxacin

Sparfloxacin is a fluoroquinolone antibiotic. Sparfloxacin is a new fluoroquinolone recently approved by FDA. Sparfloxacin is used to treat a large variety of bacterial infections, such as respiratory tract infections, middle ear infections, skin infections and urinary tract infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular intervals of time throughout the day and night as prescribed. Sparfloxacin is important to take the drug for the full time period as prescribed, discontinuation of the drug may result in ineffective treatment.

Sparfloxacin is primarily indicated in conditions like Acne, Bacterial infections, Bronchitis, Burns, Conjunctivitis, Cystitis, Dysenteries, Folliculitis, Impetigo, Otitis media, Pneumonia, Prostatitis, Pyelonephritis, Respiratory tract infections, Sinusitis, Superficial infections, Surgical infections, Tonsillitis, Urethritis.

Sparfloxacin is contraindicated in conditions like Hypersensitivity.

The severe or irreversible adverse effects of Sparfloxacin, which give rise to further complications include Anemia. The symptomatic adverse reactions produced by Sparfloxacin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Vomiting, Diarrhea, Myalgia, Anxiety, Insomnia, Abdominal pain, Rashes, Sleep disturbance, Arthralgia, Agitation, Eosinophilia, Leukopenia, Delirium.

Sparfloxacin should be used with caution in patients with any allergy, previous drug reactions (rash) to sunlight, kidney disease, heart conditions, certain mental conditions (psychosis), blood vessel disease (carotid arteries), brain disorders (e.g. seizures or cancer) or tendon problems. Exposure to direct or indirect sunlight, tanning lamps etc. should be avoided for the entire treatment period and five days beyond. Only sunscreens which block UV-A rays (e.g. octocrylene or Parsol-1789 containing products) have been effective protection, along with adequate clothing. Limit alcohol, because this drug could cause drowsiness, and alcohol can intensify drowsiness. Patient should observe caution while driving or performing tasks requiring mental alertness. It should be used only when clearly needed during pregnancy or lactation. This antibiotic is not recommended for use in persons under 18 years old. Avoid repeated or prolonged use of this medication because prolonged or repeated periods may result in a secondary infection (e.g.oral, bladder or vaginal yeast infection).

Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

100 to 200 mg (150 (150)) 12 hourly PO — Maintenance. 400 mg (400 (400)) 24 hourly PO — Initially.

( ) — Not recommended in this age group

( ) — Not recommended in this age group

Sparfloxacin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementSodium PhosphateShould not be use concurrently without doctors prescription.TheophyllineVORICONAZOLEAdditive QTc prolongation may occur. Consider alternate therapy or monitor for QTc prolongation These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Tab Store Between 20°C-25°C. Protect from Sunlight and Moisture.