Sulfadimidine
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Sulfadimidine is antibacterial, belongs to Sulphonamide. It has a broad spectrum of activity, mainly effective for urinary tract infections.
Indications
Sulfadimidine is primarily indicated in conditions like Meningitis, Urinary tract infection.
Contraindications
Sulfadimidine is contraindicated in conditions like Renal failure, Porphyrias.
Side Effects
The severe or irreversible adverse effects of Sulfadimidine, which give rise to further complications include Thrombocytopenia, Hepatitis, Pancreatitis, Cholestatic jaundice, Hemolytic anemia, Epidermal necrolysis, Vasculitis, Agranulocytosis, Iritis, Retinal hemorrhage, Optic neuropathy, Pulmonary eosinophilia, Arteritis. Sulfadimidine produces potentially life-threatening effects which include Stevens Johnson syndrome. which are responsible for the discontinuation of Sulfadimidine therapy. The symptomatic adverse reactions produced by Sulfadimidine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Fever, Rashes, Hematuria, Nausea and vomiting, Cyanosis, Leukopenia, Crystalluria, Anuria.
Warnings
Allergic reaction to sulfa drugs may occur sometimes. Elderly adults are especially sensitive to the effects of sulfonamides. Severe skin and blood disorders may be more likely to occur in the elderly. The adverse effects may also be more likely to occur in patients who are taking diuretics together with these drugs
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.5 to 1 g (0.75 (0.75)) 6 hourly PO,IM,IV — Maintenance.
2 g (2 (2)) As recommended. PO — Single dose.
Child Dosage
25 mg/kg (25 (25)) 6 hourly Intra Muscular — Maintenance, As Required
25 mg/kg (25 (25)) 6 hourly Intra Venous — Maintenance, As Required
25 mg/kg (25 (25)) 6 hourly Oral — Maintenance, As Required
50 mg/kg (50 (50)) As recommended. Intra Muscular — Initially for Once
50 mg/kg (50 (50)) As recommended. Intra Venous — Initially for Once
50 mg/kg (50 (50)) As recommended. Oral — Initially for Once
Neonatal Dosage
25 mg/kg (25 (25)) 6 hourly Intra Muscular — Maintenance, As Required
25 mg/kg (25 (25)) 6 hourly Intra Venous — Maintenance, As Required
25 mg/kg (25 (25)) 6 hourly Oral — Maintenance, As Required
50 mg/kg (50 (50)) As recommended. Intra Muscular — Initially for Once
50 mg/kg (50 (50)) As recommended. Intra Venous — Initially for Once
50 mg/kg (50 (50)) As recommended. Oral — Initially for Once
Drug Interactions
No data regarding the interactions of Sulfadimidine was found.
Storage
Tab, Susp, Inj
Available Brands in Pakistan
No active brands are currently recorded for this generic.
6 records are present but flagged "Unverified / Legacy" and excluded.