Sulphacetamide

Sulphacetamide is a synthetic sulfonamide antibiotic for ophthalmic or topical administration. Sulfacetamide, because Sulphacetamide is water soluble and because a 30% solution has a pH of 7.4, is an ideal sulfonamide for ophthalmic administration. Despite the favorable pharmaceutical properties, use of sulfonamides in general has declined due to development of resistance.

Sulphacetamide is primarily indicated in conditions like Blepharitis, Conjunctivitis, Eye infections, Vaginosis.

Sulphacetamide is contraindicated in conditions like Herpes simplex infections, Renal failure, Corneal infection.

The severe or irreversible adverse effects of Sulphacetamide, which give rise to further complications include Conjunctivitis, Skin rashes, Corneal plaques. Sulphacetamide produces potentially life-threatening effects which include Stevens Johnson syndrome, Erythema multiforme. which are responsible for the discontinuation of Sulphacetamide therapy. The symptomatic adverse reactions produced by Sulphacetamide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Blurred vision, Burning, Vaginal irritation, Stinging on application.

Consult with doctor about use of sulphacetamide during pregnancy or lactation.

Drug should not be given to patients suffering from Kidney dysfunction. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

10 to 30 % (20 (20)) 6 hourly Ophthalmic —

10 to 20 % (15 (15)) As recommended. Opthalmic — As Required

No neonatal dosage information is recorded for this medicine yet.

No data regarding the interactions of Sulphacetamide was found.

Eye Oint or Eye Soln, Skin Lotion Store in a well closed container, at room temperature, Below 15°C. Refrigeration and Freezing is not recommended. Protect from Sunlight.