Sulpiride
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Sulpiride is antipsychotic agent with similar action and uses as for chlorpromazine. Sulpiride is used in the treatment of schizophrenia, also given for the management of anxiety, vertigo and peptic ulceration.
Indications
Sulpiride is primarily indicated in conditions like Control of muscarinic side-effects of neostigmine, Depression, Psychosis, Schizophrenia.
Contraindications
Sulpiride is contraindicated in conditions like Epilepsy, Pheochromocytoma, Porphyria.
Side Effects
The severe or irreversible adverse effects of Sulpiride, which give rise to further complications include Tardive dyskinesia. Sulpiride produces potentially life-threatening effects which include Hepatitis, Malignant neuroplastic syndrome, Hypertensive crises. which are responsible for the discontinuation of Sulpiride therapy. The signs and symptoms that are produced after the acute overdosage of Sulpiride include Hypotension, Confusion, Agitation, Restlessness, Extrapyramidal effects. The symptomatic adverse reactions produced by Sulpiride are more or less tolerable and if they become severe, they can be treated symptomatically, these include Irritability, Excitement, Anxiety, Parkinsonism, Akathisia, Acute dystonia, Elevated alkaline phosphatase, Mood swings, Leukopenia, Elevated aminotransferase.
Warnings
Sulpiride should be given with care to manic or hypomanic patients in whom it may exacerbate symptoms. It should be used with care during pregnancy, avoid use during lactation. It should be used with caution in patients with impaired renal function.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
200 to 400 mg (300 (300)) 12 hourly PO — Max.800 mg daily.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
Not indicated in this age group ( ) —
Drug Interactions
Sulpiride is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholAmitriptyline (HCl)Buspirone (HCl)Cimetidine (HCl)Clomipramine (HCl)CocainedeferoxamineDisulfiramNaltrexonePiperazineSucralfate These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab Store Below 25°C.
Available Brands in Pakistan
No active brands are currently recorded for this generic.
2 records are present but flagged "Unverified / Legacy" and excluded.