Telithromycin

It is used to treat bacterial infections.

It is used to treat bacterial infections.

Telithromycin is contraindicated in conditions like Breast feeding.

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Very bad dizziness or passing out. Fast or slow heartbeat. A heartbeat that does not feel normal. Any unexplained bruising or bleeding. Change in eyesight. Feeling confused. Hallucinations (seeing or hearing things that are not there). Muscle weakness. Vaginal itching or discharge. Diarrhea is common with antibiotics . Rarely, a severe form called C diff–associated diarrhea (CDAD) may happen. Sometimes, this has led to a deadly bowel problem (colitis). CDAD may happen during or a few months after taking antibiotics. Call your doctor right away if you have stomach pain, cramps, or very loose, watery, or bloody stools. Check with your doctor before treating diarrhea. Very bad and sometimes deadly liver problems have happened with telithromycin. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.

Telithromycin should be used with caution in hepatic impairment; renal impairment (use half normal dose if creatinine clearance less than 30ml/min); pregnancy (use only if potential benefit outweighs risk); coronary heart disease, ventricular arrhythmias, brady cardia, hypokalemia, hypomagnesaemia, risk of QT interval prolongation; concomitant administration of drug that prolong QT interval. Arrhythmias: Avoid concomitant administration with pimozide or terfenadine.

Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, and patients suffering from Kidney dysfunction. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

800 mg (800 (800)) 24 hourly PO — For 5 days for Beta-hemolytic streptococcal pharyngitis or tonsilitis.

No child dosage information is recorded for this medicine yet.

No neonatal dosage information is recorded for this medicine yet.

Telithromycin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCarbamazepineCarbamazepine is likely to result in subtherapeutic levels of telithromycin and loss of effect.CisaprideThe use of Teicoplanin is contraindicated with cisapride.Clorazepate (K)DigoxinMonitoring of digoxin side effects or serum levels should be considered during concomitant administration of digoxin and Teicoplanin.ErlotinibThis CYP3A4 inhibitor increases levels/toxicity of erlotinibPhenobarbitonePhenobarbitone is likely to result in subtherapeutic levels of telithromycin and loss of effect.Phenytoin (Na)Phenytoin (Na) is likely to result in subtherapeutic levels of telithromycin and loss of effect.PimozideThere is a potential risk of increased pimozide plasma levels by inhibition of CYP 3A4 pathways by Teicoplanin. Concurrent use is contraindicated.SimvastatinSimvastatin levels were increased by Teicoplanin when used concurrently.SunitinibMay increases sunitinib concentrations.VemurafenibTelithromycin inhibits P-gp, glucuronidation and CYP3A4, and increases plasma concentration of Vemurafenib.VORICONAZOLEVoriconazole may increase the serum concentration of telithromycin by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

No storage information is recorded for this medicine yet.