Tenecteplase
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Tenecteplase is used in adults to treat a stroke caused by a clot (acute ischemic stroke ) and to lower the risk of death from a certain type of heart attack .
Tenecteplase may also be used for purposes not listed in this medication guide.
Indications
Tenecteplase is used in adults to treat a stroke caused by a clot (acute ischemic stroke ) and to lower the risk of death from a certain type of heart attack .
Tenecteplase may also be used for purposes not listed in this medication guide.
Contraindications
Do not use this medicine for a stroke if you have bleeding in your brain now, or for heart attack if you ever had bleeding in your brain or an ischemic stroke in the last 3 months.
You should not be treated with tenecteplase if you are allergic to it, or if you have:
active bleeding inside your body; severe or uncontrolled high blood pressure; certain brain conditions that increase bleeding risk (such as a brain tumor, an aneurysm, or other abnormal blood vessel problems); a bleeding or blood clotting disorder (such as hemophilia ); or if you had brain or spine injury or surgery within the past 2 months.
If possible before you receive tenecteplase, tell your doctor if you have ever had:
bleeding in your brain, stomach, intestines, or urinary tract; heart problems, high blood pressure; history of stroke; an infection of the lining of your heart (subacute bacterial endocarditis ); inflammation around the heart (acute pericarditis ); if you are using a blood thinner or medicine used to prevent blood clots; bleeding in the eye caused by diabetes or other eye problems; severe inflammation or infection around a vein where an IV was placed; a recent serious injury, surgery, or procedure (for example, heart bypass, organ biopsy, or puncture of a large blood vessel); or severe liver or kidney disease.
If possible during an emergency, tell your medical caregivers if you are pregnant, recently delivered a baby, or are breastfeeding.
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Tenecteplase increases your risk of bleeding even 1 or more days after receiving tenecteplase, which can be severe or life-threatening. Get emergency medical help if bleeding will not stop.
Tenecteplase may cause serious side effects. Call your doctor at once if you have:
easy bruising or bleeding (nosebleeds, bleeding gums, bleeding from a wound, incision, catheter, or injection site); bleeding inside your body --weakness, pink or brown urine, abnormal vaginal bleeding, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; signs of a stroke --sudden numbness or weakness (especially on one side of the body), severe headache, slurred speech, problems with vision or balance; signs of a blood clot in the lung --chest pain, sudden cough or shortness of breath , dizziness, coughing up blood; signs of a blood clot deep in the body --pain, swelling, or warmth in one leg; or very slow or fast heartbeats, shortness of breath, or feeling light-headed.
Common side effects of tenecteplase may include:
bleeding.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
If possible before you receive tenecteplase, tell your doctor if you have or have ever had: high blood pressure , active bleeding or bleeding in your brain, bleeding disorder , any brain blood vessel problem (such as an aneurysm), brain tumor , past stroke, or a recent surgery or injury on your brain or spine.
If you receive tenecteplase during an emergency, make sure any follow-up doctor knows you received tenecteplase.
Tenecteplase can cause serious, sometimes life-threatening bleeding. Call your doctor or seek emergency medical help if you have any bleeding that will not stop.
High Risk Groups
If possible before you receive tenecteplase, tell your doctor if you have or have ever had: high blood pressure , active bleeding or bleeding in your brain, bleeding disorder , any brain blood vessel problem (such as an aneurysm), brain tumor , past stroke, or a recent surgery or injury on your brain or spine.
If you receive tenecteplase during an emergency, make sure any follow-up doctor knows you received tenecteplase.
Tenecteplase can cause serious, sometimes life-threatening bleeding. Call your doctor or seek emergency medical help if you have any bleeding that will not stop.
Adult Dosage
No adult dosage information is recorded for this medicine yet.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Tell your doctor about all your other medicines, especially:
a blood thinner --heparin, warfarin, Coumadin, Jantoven; medicine used to prevent blood clots --alteplase, clopidogrel , dipyridamole , ticlopidine , and others; or NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib , diclofenac , indomethacin , meloxicam , and others.
This list is not complete. Other drugs may affect tenecteplase, including prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible drug interactions are listed here.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.