Thiabendazole
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Thiabendazole is a broad spectrum anthelmintic agent. Thiabendazole is a benzimidazole compound. It has vermicidal activity against roundworm, whipworm and hookworm. It also has anti-inflammatory properties, antipyretic, mild antifungal and scabicidal actions.
Indications
Thiabendazole is primarily indicated in conditions like Helminth infection.
Contraindications
Thiabendazole is contraindicated in conditions like Hypersensitivity to any component of product.
Side Effects
Thiabendazole produces potentially life-threatening effects which include Stevens Johnson syndrome, Jaundice. which are responsible for the discontinuation of Thiabendazole therapy. The symptomatic adverse reactions produced by Thiabendazole are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Drowsiness, Nausea, Vomiting, Anorexia, Tinnitus, Blurred vision, Pruritus, Elevated hepatic transaminases, Leukopenia, Paresthesias, GI irritation.
Warnings
Thiabendazole should be used with caution in patients with kidney or liver disease. Patient should observe caution while driving or performing tasks requiring alertness.
High Risk Groups
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
25 mg/kg (25 (25)) 12 hourly PO — -
Child Dosage
25 mg/kg (25 (25)) 12 hourly Oral — -
Neonatal Dosage
25 mg/kg (25 (25)) 12 hourly Oral — -
Drug Interactions
Thiabendazole is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAminophyllineOxtriphylline (Choline Theophyllinate)TheophyllineTheophylline These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab, Susp Store Below 25°C. Protect from Sunlight.
Available Brands in Pakistan
No brands are recorded for this generic.