Tinzaparin Sodium

Tinzaparin is used for the treatment of deep venous thrombosis, a condition in which harmful blood clots form in the blood vessels of the legs. These blood clots can travel to the lungs and can become lodged in the blood vessels of the lungs, causing a condition called pulmonary embolism. Tinzaparin is used for several days after surgery, while you are unable to walk. It is during this time that blood clots are most likely to form. Tinzaparin also may be used for other conditions as determined by your doctor. This medicine is available only with your doctor's prescription.

Tinzaparin is used for the treatment of deep venous thrombosis, a condition in which harmful blood clots form in the blood vessels of the legs. These blood clots can travel to the lungs and can become lodged in the blood vessels of the lungs, causing a condition called pulmonary embolism. Tinzaparin is used for several days after surgery, while you are unable to walk. It is during this time that blood clots are most likely to form. Tinzaparin also may be used for other conditions as determined by your doctor. This medicine is available only with your doctor's prescription.

Tinzaparin Sodium is contraindicated in conditions like Heparin induced thrombocytopenia, Hypersensitivity to any component of product.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Deep, dark purple bruise, pain, or swelling at the place of injection Less common Bladder pain bleeding gums blood in the urine bloody or cloudy urine blurred vision chest pain chest tightness chills confusion cough coughing up blood difficulty with breathing or swallowing dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position fast, slow, or irregular heartbeat fever frequent urge to urinate headache increased menstrual flow or vaginal bleeding lower back or side pain nosebleeds pain or burning while urinating painful or difficult urination pale skin palpitations paralysis pounding in the ears prolonged bleeding from cuts red or black, tarry stools red or dark brown urine severe or continuing dull nervousness shortness of breath skin rash sore throat sores, ulcers, or white spots on the lips or in the mouth sweating swollen glands troubled breathing, exertional unexplained pain, swelling, or discomfort, especially in the chest, abdomen or stomach, joints, or muscles unusual bleeding or bruising unusual tiredness or weakness vomiting of blood or material like coffee grounds Rare Blue-green to black skin discoloration bowel or bladder dysfunction hives itching leg weakness numbness pain, redness, or sloughing of the skin at the place of injection puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue wheezing Incidence not known Abdominal or stomach pain accumulation of pus break in the skin, especially associated with blue-black discoloration, swelling, or drainage of fluid change in vision clay-colored stools collection of blood under the skin diarrhea excessive thirst general feeling of discomfort or illness hoarseness large, flat, blue or purplish patches in the skin large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs loss of appetite muscle cramps numbness and tingling of the face, fingers, or toes pain in the arms, legs, or lower back, especially pain in the calves or heels upon exertion pain, redness, or swelling painful knees and ankles pale, bluish-colored, or cold hands or feet problems with vision or hearing raised, red swellings on the skin, buttocks, legs or ankles red or irritated eyes redness, tenderness, burning, blistering, or peeling of the skin (usually on the backs of arms and the fronts of legs, mouth, eyes, hands, or feet) seeing floating spots before the eyes swollen, red, or tender area of infection unpleasant breath odor weak or absent pulses in the legs yellow eyes or skin Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common or rare Constipation nausea and vomiting prolonged, painful, or inappropriate erection of the penis trouble with sleeping Incidence not known Hives or welts redness of the skin Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Should not be mixed with other injections or infusions. Should be used with care in patients with a bleeding diathesis, uncontrolled arterial hypertension, or a history of recent gastrointestinal ulceration, diabetic retinopathy and hemorrhage. Tinzaparin Sodium contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown, but is probably low. Sulfite sensitivity is more frequent in asthmatic people than in non-asthmatic people.

Drug should not be given to Cardiac / Hypertensive Patients, and Geriatrics. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

175 anti-Xa IU/kg of body weight (180 (175)) 24 hourly SC — Should be administered for at least 6 days and until the patient is adequately anticoagulated with warfarin (INR at least 2.0 for two consecutive days). Warfarin sodium therapy should be initiated when appropriate (usually within 1-3 days of Tinzaparin Sodium initiation).

No child dosage information is recorded for this medicine yet.

No neonatal dosage information is recorded for this medicine yet.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Defibrotide Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Abciximab Aceclofenac Acemetacin Acenocoumarol Alipogene Tiparvovec Alteplase, Recombinant Amtolmetin Guacil Anagrelide Anistreplase Antithrombin, Recombinant Apixaban Argatroban Aspirin Bemiparin Betrixaban Bivalirudin Bromfenac Bufexamac Caplacizumab-yhdp Celecoxib Choline Salicylate Citalopram Clonixin Clopidogrel Collagenase, Clostridium histolyticum Curcumin Dabigatran Etexilate Dalteparin Danaparoid Desvenlafaxine Dexibuprofen Dexketoprofen Dextran Diclofenac Diflunisal Dipyridamole Dipyrone Drotrecogin Alfa Droxicam Edoxaban Enoxaparin Eptifibatide Escitalopram Etodolac Etofenamate Etoricoxib Felbinac Fenoprofen Fepradinol Feprazone Floctafenine Flufenamic Acid Fluoxetine Flurbiprofen Fluvoxamine Ibrutinib Ibuprofen Ibuprofen Lysine Iloprost Indomethacin Inotersen Ketoprofen Ketorolac Lepirudin Levomilnacipran Lornoxicam Loxoprofen Lumiracoxib Meclofenamate Mefenamic Acid Meloxicam Milnacipran Morniflumate Nabumetone Nadroparin Naproxen Nepafenac Niflumic Acid Nimesulide Nimesulide Beta Cyclodextrin Nintedanib Omadacycline Orlistat Oxaprozin Oxyphenbutazone Parecoxib Paroxetine Pentosan Polysulfate Sodium Phenindione Phenprocoumon Phenylbutazone Piketoprofen Piracetam Piroxicam Prasugrel Proglumetacin Propionic Acid Propyphenazone Proquazone Reteplase, Recombinant Rivaroxaban Rofecoxib Salicylic Acid Salsalate Sarecycline Sertraline Sodium Salicylate Streptokinase Sulfinpyrazone Sulindac Tenecteplase Tenoxicam Tiaprofenic Acid Ticlopidine Tirofiban Tolfenamic Acid Tolmetin Trazodone Treprostinil Turmeric Urokinase Valdecoxib Venlafaxine Vilazodone Vorapaxar Vortioxetine Warfarin

Inj Store in a well closed container, Between 15°C-30°C. Protect from Sunlight, Moisture and Heat.