Tobramycin

Tobramycin is an aminoglycoside (ah-meen-oh-GLY-ko-side) antibiotic. Tobramycin fights infections that are caused by bacteria. Tobramycin injection is used to treat bacterial infections of the skin, heart, stomach, brain and spinal cord, lungs, and urinary tract (bladder and kidneys). It is also used in the treatment of cystic fibrosis . Tobramycin injection is sometimes used together with other antibiotics . Tobramycin may also be used for purposes not listed in this medication guide.

Tobramycin is an aminoglycoside (ah-meen-oh-GLY-ko-side) antibiotic. Tobramycin fights infections that are caused by bacteria. Tobramycin injection is used to treat bacterial infections of the skin, heart, stomach, brain and spinal cord, lungs, and urinary tract (bladder and kidneys). It is also used in the treatment of cystic fibrosis . Tobramycin injection is sometimes used together with other antibiotics . Tobramycin may also be used for purposes not listed in this medication guide.

You should not use this medication if you are allergic to tobramycin or similar antibiotics (amikacin, gentamicin, kanamycin, neomycin, paromomycin , streptomycin ). To make sure tobramycin injection is safe for you, tell your doctor if you have: kidney disease; a muscle disorder such as myasthenia gravis ; Parkinson's disease ; asthma; or a metabolic disorder such as high or low levels of potassium, calcium, or magnesium in your blood. FDA pregnancy category D. Do not use tobramycin if you are pregnant. It could harm the unborn baby. Use effective birth control , and tell your doctor if you become pregnant during treatment. Tobramycin can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Serious side effects may be more likely in older adults.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Tobramycin can damage nerves and may cause hearing loss that may be permanent. Tell your doctor right away if you have: numbness, tingling, muscle stiffness or uncontrolled twitching; dizziness, spinning sensation, seizure (convulsions); or hearing loss , or a ringing or roaring sound in your ears (even after you have stopped using tobramycin injection). Tobramycin may cause serious side effects. Call your doctor at once if you have: swelling, rapid weight gain, little or no urinating; confusion, loss of appetite, vomiting, pain in your side or lower back; fever; or severe skin reaction -- fever, sore throat , swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling. Common side effects of tobramycin may include: headache; lack of energy; mild rash or itching; nausea, vomiting, diarrhea; or pain where the medicine was injected. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tobramycin can damage nerves and may cause hearing loss that may be permanent. Call your doctor right away if you have numbness, tingling, muscle twitching , dizziness, spinning sensation, seizure (convulsions), hearing loss, or a ringing or roaring sound in your ears (even after you have stopped using tobramycin injection). Tobramycin can also harm your kidneys , and this effect is increased when you also use certain other medicines harmful to the kidneys. Tell your doctor about all other medications you use , especially injected antibiotics.

Tobramycin can damage nerves and may cause hearing loss that may be permanent. Call your doctor right away if you have numbness, tingling, muscle twitching , dizziness, spinning sensation, seizure (convulsions), hearing loss, or a ringing or roaring sound in your ears (even after you have stopped using tobramycin injection). Tobramycin can also harm your kidneys , and this effect is increased when you also use certain other medicines harmful to the kidneys. Tell your doctor about all other medications you use , especially injected antibiotics.

0.3 % w/v (0.3 (0.3)) 6 hourly Ophthalmic, Otic — 3 to 5 mg/ kg (4 (4)) As recommended. IM,Slow IV — In 3-4 divided doses.

2 to 2.5 mg/kg (2.2 (2.25)) 8 hourly Intra Muscular — - 2 to 2.5 mg/kg (2.2 (2.25)) 8 hourly Intra Venous — -

2 to 2.5 mg/kg (2.2 (2.25)) 8 hourly Intra Muscular — - 2 to 2.5 mg/kg (2.2 (2.25)) 8 hourly Intra Venous — -

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with tobramycin, especially: diuretics -- ethacrynic acid , furosemide . Tobramycin can harm your kidneys. This effect is increased when you also use certain other medicines, especially: cisplatin; injected antibiotics --amikacin, colistimethate , kanamycin, gentamicin, polymyxin B , streptomycin, vancomycin; or certain antibiotics taken by mouth --neomycin, paromomycin. This list is not complete. Other drugs may interact with tobramycin, including prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible interactions are listed in this medication guide.

Eye Drops, Oint, Inj Store at room temperature or refrigerator. Protect from Sunlight.