Topiramate

Topiramate is an anticonvulsant medication used to treat seizures , including partial-onset or primary generalized tonic-clonic seizures in adults and children who are at least 2 years old, as monotherapy. It can be used with other medicines to treat partial-onset seizures, primary generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome in adults and children 2 years and older. Topiramate reduces the frequency and duration of seizures. Topiramate is also used to prevent migraine headaches in adults and teenagers who are at least 12 years old. This medicine helps to prevent migraine headaches or reduce the number of attacks; it will not treat a headache that has already begun. Topiramate has also been used off-label for binge eating disorder (BED), alcohol dependence, and essential tremor. Topiramate brand names are Topamax , Eprontia , Qudexy XR , and Trokendi XR . Generic topiramate is also available. Topiramate and phentermine are the active ingredients in Qsymia, an appetite suppressant used for weight loss. Topiramate FDA approval was first granted on December 24, 1996, for the Topamax brand by Jansen Pharmaceuticals.

Topiramate is an anticonvulsant medication used to treat seizures , including partial-onset or primary generalized tonic-clonic seizures in adults and children who are at least 2 years old, as monotherapy. It can be used with other medicines to treat partial-onset seizures, primary generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome in adults and children 2 years and older. Topiramate reduces the frequency and duration of seizures. Topiramate is also used to prevent migraine headaches in adults and teenagers who are at least 12 years old. This medicine helps to prevent migraine headaches or reduce the number of attacks; it will not treat a headache that has already begun. Topiramate has also been used off-label for binge eating disorder (BED), alcohol dependence, and essential tremor. Topiramate brand names are Topamax , Eprontia , Qudexy XR , and Trokendi XR . Generic topiramate is also available. Topiramate and phentermine are the active ingredients in Qsymia, an appetite suppressant used for weight loss. Topiramate FDA approval was first granted on December 24, 1996, for the Topamax brand by Jansen Pharmaceuticals.

You should not use this medication if you are allergic to topiramate. You should not drink alcohol while taking this medicine. Tell your doctor if you are sick with diarrhea , or if you have ever had: glaucoma or other eye problems; metabolic acidosis (high levels of acid in your blood); kidney disease, kidney stones , or dialysis; lung disease, breathing problems; mood problems, depression , or suicidal thoughts or actions; Liver problems; a growth disorder; soft or brittle bones ( osteoporosis , osteomalacia); have diarrhea; are on a diet high in fat and low in carbohydrates, which is called a ketogenic diet; or are having surgery Topiramate can increase the level of acid in your blood (metabolic acidosis). This can weaken your bones, cause kidney stones, or cause growth problems in children or harm to an unborn baby. You may need blood tests to make sure you do not have metabolic acidosis, especially if you are pregnant. Some people have thoughts about suicide while taking an anticonvulsant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

The symptomatic adverse reactions produced by Topiramate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Decrease in serum bicarbonate, Dizziness, Ataxia, Nervousness, Confusion, Pharyngitis, Depression, Edema, Hot flushes, Somnolence, Chest pain, Backache, Rigors, Xerostomia, Speech problems, Psychomotor slowing, Abnormal vision, Decreased memory, Injury, Weight loss, Abnormal gait, Mood problems, Menorrhagia.

Topiramate may cause vision problems that can be permanent if not treated quickly. Call your doctor right away if you have a sudden decrease in vision. Topiramate can increase body temperature and decrease sweating, which may lead to life-threatening dehydration . Tell your doctor if you have decreased sweating, high fever, and hot dry skin. Some people have thoughts about suicide while taking seizure medicine. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor. Do not stop using topiramate suddenly or you could have increased seizures.

Topiramate may cause vision problems that can be permanent if not treated quickly. Call your doctor right away if you have a sudden decrease in vision. Topiramate can increase body temperature and decrease sweating, which may lead to life-threatening dehydration . Tell your doctor if you have decreased sweating, high fever, and hot dry skin. Some people have thoughts about suicide while taking seizure medicine. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor. Do not stop using topiramate suddenly or you could have increased seizures.

200 mg (200 (200)) 12 hourly PO — Scraped Dose — Take topiramate exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Topiramate can be taken with or without food. Swallow the tablets whole and do not crush, chew, or break a tablet. If you cannot swallow a Topamax Sprinkle Capsule whole, open the capsule and sprinkle the medicine into a spoonful of applesauce or other soft food. Swallow the mixture right away without chewing. Do not save it for later use. Carefully follow the swallowing instructions for your medicine. Topiramate doses are sometimes based on weight in children. Your child's dose needs may change if the child gains or loses weight. Drink plenty of liquids while you are taking this medicine to prevent kidney stones or an electrolyte imbalance. You will need frequent medical tests. If you need surgery, tell the surgeon ahead of time that you are using topiramate. Any medical care provider who treats you should know that you take seizure medication. Do not stop using this medicine suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose. Call your doctor if your seizures get worse or you have them more often while taking topiramate. Store at cool room temperature away from moisture, light, and high heat.

( ) — Not recommended in this age group 2.5 to 4.5 mg/kg (3.5 (3.5)) 12 hourly Oral — Maintenance.Gradually increase the dose

( ) — Not recommended in this age group

Using topiramate with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or depression. Tell your doctor about all your other medicines, especially: zonisamide ; birth control pills; divalproex, valproic acid ; or other glaucoma medications, including eye drops. This list is not complete. Other drugs may interact with topiramate, including prescription and over-the-counter medicines, vitamins , and herbal products . Not all possible drug interactions are listed here.

Tab Store Below 40°C. Protect from Sunlight and Moisture.