Treosulfan
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Treosulfan is used in adults and children at least 1 year old with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) as preparation for a stem cell transplant.
Treosulfan is used in combination with other cancer treatments.
Treosulfan may also be used for purposes not listed in this medication guide.
Indications
Treosulfan is used in adults and children at least 1 year old with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) as preparation for a stem cell transplant.
Treosulfan is used in combination with other cancer treatments.
Treosulfan may also be used for purposes not listed in this medication guide.
Contraindications
You should not be treated with treosulfan if you are allergic to it.
Tell your doctor if you have or have ever had:
an active or recent infection; seizures; an organ transplant , or a stem cell transplant from a donor; or chemotherapy or radiation.
Using treosulfan may increase your risk of developing other cancers. Ask your doctor about this risk.
Treosulfan can harm an unborn baby if the mother or the father is receiving treosulfan.
If you are a woman, you may need a pregnancy test to make sure you are not pregnant. Use birth control while using this medicine and for at least 6 months after your last dose. If you are a man, use birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose. Tell your doctor right away if a pregnancy occurs.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
Treosulfan may affect fertility in men or women. Pregnancy could be harder to achieve while either parent is using this medicine.
Side Effects
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Treosulfan may cause serious side effects. Call your doctor at once if you have:
swelling, pain, burning, irritation, or skin changes where the injection was given; severe itching , rash, or dryness of the skin; unusual bruising or bleeding, new signs of infection (fever, weakness, cough , diarrhea , burning when you urinate); or seizures .
Common side effects of treosulfan may include:
infections, fever; mouth sores; muscle, bone, or joint pain ; nausea or vomiting ; swelling; or abnormal lab results.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You may get infections, even serious infections, or bleed more easily. Call your doctor if you have flu symptoms, fever, skin sores, cough, night sweats, neck stiffness, confusion, or vision problems.
High Risk Groups
You may get infections, even serious infections, or bleed more easily. Call your doctor if you have flu symptoms, fever, skin sores, cough, night sweats, neck stiffness, confusion, or vision problems.
Adult Dosage
3.571 mg/kg (3.6 (3.571)) 6 hourly PO — -
71.429 to 214.286 mg/kg (140 (142.8575)) As recommended. Slow IV — Every 1-3 Week
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Other drugs may affect treosulfan, including prescription and over-the-counter medicines, vitamins , and herbal products . Tell your doctor about all other medicines you use.
Storage
Cap, IV Inj, IV Inf
Available Brands in Pakistan
No brands are recorded for this generic.