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Medicines/Generics/Triprolidine (HCl)

Triprolidine (HCl)

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview
Triprolidine (HCl) is antihistamine. Triprolidine (HCl) is effective in the symptomatic treatment of seasonal and perennial allergic rhinitis, allergic conjunctivitis and uncomplicated skin manifestation of urticaria etc.
Indications
Triprolidine (HCl) is primarily indicated in conditions like Allergic conjunctivitis, Allergic rhinitis, Angioedema, Common cold, Fever, Urticaria.
Contraindications
Triprolidine (HCl) is contraindicated in conditions like Alcohol dependence, Prostatic hypertrophy, Narrow-angle glaucoma, Hypersensitivity.
Side Effects
The signs and symptoms that are produced after the acute overdosage of Triprolidine (HCl) include Convulsions, Respiratory depression, Dizziness, Incoordination, Weakness. The symptomatic adverse reactions produced by Triprolidine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Drowsiness, Anorexia, Palpitation, Tinnitus, Blurred vision, Confusion, Epigastric discomfort, Dysuria, Photosensitivity, Postural hypotension, Skin eruptions, Somnolence, Urinary frequency, GI disturbance, Lassitude.
Warnings
Triprolidine should be used with caution in patients with asthma, glaucoma, ulcer, difficulty urinating due to an enlarged prostate gland, heart disease, high blood pressure, seizures or hyperthyroidism. Do not drink alcoholic beverages. This drug should be used only if clearly needed during pregnancy or lactation. Do not give this medication to a child younger than six years of age unless directed to do so by a doctor.
High Risk Groups
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
25 to 50 mg (38 (37.5)) 8 hourly PO — Frequency may be increased upto 4 times/day if needed.
Child Dosage
0.2 mg/kg (0.2 (0.2)) 8 hourly Oral — -
Neonatal Dosage
0.125 mg/kg (0.12 (0.125)) 8 hourly Oral —
Drug Interactions
Triprolidine (HCl) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholClemastineDipipanone (HCl)GlycopyrrolateSodium AcetateAlkalization of the urine decreases the urinary excretion increases the elimination half-life of Triprolidine (HCl).ModeratePatients should be monitored for toxic effects such as tremor, anxiety, insomnia, irritability, or nervousness. Dosage reductions may be required. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab, Syrup Store Below 40°C. Protect from Sunlight and Moisture.

Available Brands in Pakistan

2 active brands listed alphabetically.

ACTIDIL

Active

GLAXOSMITHKLINE

DML: ACTIDIL

TabsElixir

ACTIVE P

Active

PROGRESSIVE LABORATORIES

DML: ACTIVE P

Tabs

1 additional record is present but flagged "Unverified / Legacy" and not listed.