Medicines/Generics/Urofollitrophin

Urofollitrophin

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Urofollitrophin or Urofollitropin is a follicle-stimulating hormone, extracted from human post-menopausal urine. It stimulates the ovulation in female and spermatogenesis in male.

Indications

Urofollitrophin is primarily indicated in conditions like Induction of ovulation, Polycystic ovary syndrome, Spermatogenesis.

Contraindications

Urofollitrophin is contraindicated in conditions like Ovarian failure, Ovarian dysgenesis, Ovarian cysts, Pregnancy.

Side Effects

The severe or irreversible adverse effects of Urofollitrophin, which give rise to further complications include Hyperstimulation syndrome. Urofollitrophin produces potentially life-threatening effects which include Electrolyte and volume depletion, Oliguria, Ovarian enlargement, Ascites, Pleural effusion, Abdominal distention. which are responsible for the discontinuation of Urofollitrophin therapy.The symptomatic adverse reactions produced by Urofollitrophin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Rashes, Urticaria, Hair loss, Dry skin, Breast tenderness, GI disturbance.

Warnings

It should only be used by physicians who are thoroughly familiar with infertility problems and their managements. It's use require appropriate monitoring facilitate.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Adult Dosage

150 to 225 IU (190 (187.5)) 24 hourly IM,SC — Alone in combination with GnRH. 75 to 150 IU (110 (112.5)) 24 hourly IM — Followed by 5000-10,000U 1 day after the last dose.

Child Dosage

Not applicable in paeds ( ) —

Neonatal Dosage

Not applicable in this age group ( ) —

Drug Interactions

No data regarding the interactions of Urofollitrophin was found.

Storage

Inj Store Below 25°C. Protect from Sunlight.