Medicines/Generics/Xylometazoline (HCl)

Xylometazoline (HCl)

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Chemically Xylometazoline (HCl) is 2-(4-tert-butyl-2, 6-dimethylbenzyl)-2-imidazoline hydrochloride. Xylometazoline (HCl) is a direct acting alpha-adrenoceptor agonist, used as vasoconstrictor for nasal decongestion. It promotes nasal drainage and relieves nasal stuffiness. Xylometazoline (HCl) is used to relieve symptoms associated with a cold, hay fever, allergies, sinus infections and other related conditions.

Indications

Xylometazoline (HCl) is primarily indicated in conditions like Nasal congestion.

Contraindications

Xylometazoline (HCl) is contraindicated in conditions like Diabetes mellitus, Hypertension, Narrow-angle glaucoma, Vasomotor rhinitis, Atrophic rhinitis.

Side Effects

The severe or irreversible adverse effects of Xylometazoline (HCl), which give rise to further complications include Rhinitis medicamentosa. The symptomatic adverse reactions produced by Xylometazoline (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Stinging on application, Dryness of eye, Dryness of nose, Anxiety, Dizzy, Tremor.

Warnings

Use topical decongestant (xylometazoline) only in acute conditions, not longer than 3 to 5 days. It should be used sparingly in all patients, especially in infants, children and in cardiac patients.

High Risk Groups

Drug should not be given to Pediatrics, Neonates, and Pregnant Mothers. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Adult Dosage

0.1 % (0.1 (0.1)) 8 hourly Intra Nasal — 2-3 drops in each nostril.

Child Dosage

0.1 to 0.15 mg (0.12 (0.125)) 8 hourly Opthalmic — -

Neonatal Dosage

( ) — Not recommended in this age group

Drug Interactions

No data regarding the interactions of Xylometazoline (HCl) was found.

Storage

Nasal Spray Store Below 40°C. Do not Freeze.