Ziprasidone
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Ziprasidone is an antipsychotic medicine.
Ziprasidone oral is used to treat schizophrenia and the manic symptoms of bipolar disorder ( manic depression ).
Ziprasidone injection is used to quickly treat agitation in people with schizophrenia.
Ziprasidone may also be used for purposes not listed in this medication guide.
Indications
Ziprasidone is an antipsychotic medicine.
Ziprasidone oral is used to treat schizophrenia and the manic symptoms of bipolar disorder ( manic depression ).
Ziprasidone injection is used to quickly treat agitation in people with schizophrenia.
Ziprasidone may also be used for purposes not listed in this medication guide.
Contraindications
You should not use this medicine if you are allergic to ziprasidone, or if you have:
a heart rhythm disorder; long QT syndrome (in you or a family member); uncontrolled or untreated heart failure; or if you have recently had a heart attack.
Ziprasidone can cause a serious heart problem. Your risk may be higher if you also use certain other medicines. Your doctor may change your treatment plan if you also use:
an antidepressant; bronchodilator asthma medication; cancer medicine; certain medicines for infections; heart or blood pressure medication; medicine to treat or prevent malaria; medicine to prevent nausea or vomiting; medicine to treat a psychiatric disorder; or medicine to treat HIV or AIDS.
Ziprasidone may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.
Tell your doctor if you have ever had:
any heart problems; a heart attack or stroke; fainting spells; breast cancer ; low blood levels of potassium or magnesium; diabetes (ziprasidone may raise your blood sugar); seizures or epilepsy; suicidal thoughts; Alzheimer's disease ; trouble swallowing; liver disease ; or kidney disease.
Taking antipsychotic medicine in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn . If you get pregnant, tell your doctor right away. Do not stop taking ziprasidone without your doctor's advice.
You should not breastfeed while using this medicine.
Older adults may be more sensitive to the effects of this medicine.
Ziprasidone is not approved for use by anyone younger than 18 years old.
Side Effects
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat , burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.
Ziprasidone may cause serious side effects. Stop using ziprasidone and call your doctor at once if you have:
fast or pounding heartbeats, fluttering in your chest, shortness of breath , and sudden dizziness (like you might pass out); uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); any skin rash, no matter how mild; low white blood cell counts --fever, mouth sores, skin sores, sore throat, cough, trouble breathing; high blood sugar --increased thirst, increased urination, dry mouth , fruity breath odor; or severe nervous system reaction --very stiff (rigid) muscles, high fever, sweating, confusion, agitation.
Common side effects of ziprasidone may include:
dizziness, drowsiness , weakness; headache; nausea, vomiting; trouble swallowing; weight gain; feeling restless or being unable to sit still; tremors, involuntary muscle movements; vision problems; or runny nose, new or worsening cough.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You should not use ziprasidone if you have a heart rhythm disorder, long QT syndrome , uncontrolled heart failure , or if you have recently had a heart attack .
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
Stop taking ziprasidone and call your doctor right away if you have sudden dizziness, fast or pounding heartbeats, fluttering in your chest, shortness of breath, or a new or worsening skin rash with fever, or swollen glands.
Ziprasidone is not approved for use in older adults with dementia-related psychosis.
High Risk Groups
You should not use ziprasidone if you have a heart rhythm disorder, long QT syndrome , uncontrolled heart failure , or if you have recently had a heart attack .
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
Stop taking ziprasidone and call your doctor right away if you have sudden dizziness, fast or pounding heartbeats, fluttering in your chest, shortness of breath, or a new or worsening skin rash with fever, or swollen glands.
Ziprasidone is not approved for use in older adults with dementia-related psychosis.
Adult Dosage
10 to 40 mg (25 (25)) 12 hourly IM — Patient sholud switch therapy as soon as possible.
20 to 160 mg (90 (90)) 12 hourly ORAL — Given every 2 days.
Scraped Dose — Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Ziprasidone oral is taken by mouth.
Ziprasidone injection is injected into a muscle. A healthcare provider will give you this injection if you are unable to take the medicine by mouth.
Take ziprasidone with food. Swallow the capsule whole.
You may need frequent medical tests.
If you are diabetic , check your blood sugar levels on a regular basis while you are taking ziprasidone.
It may take several weeks before your symptoms improve. Do not stop using ziprasidone suddenly , even if you feel fine. Keep using the medication as directed and tell your doctor if your symptoms do not improve.
Store at room temperature away from moisture, light, and heat.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Ziprasidone can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure , depression , mental illness, cancer, malaria, or HIV.
Using ziprasidone with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Many drugs can affect ziprasidone, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible interactions are listed here.
Storage
Store in a well closed container. Protect from Moisture and Heat.
Available Brands in Pakistan
3 active brands listed alphabetically.
XEPEX
ActiveGENETICS PHARMACEUTICALS
DML: XEPEX
Caps
ZELDOX
ActivePFIZER LABORATORIES LTD.
DML: ZELDOX
Caps
ZIPRAWIN
ActiveAMARANT PHARMACEUTICALS (PVT)
DML: ZIPRAWIN
CapsTabs
13 additional records are present but flagged "Unverified / Legacy" and not listed.
