Acute Fatty Liver of Pregnancy
Not yet clinically reviewed
This protocol was migrated from the earlier Pharmapedia and Ward Guide apps for educational use. Follow your hospital's own policies and consult seniors when in doubt.
- Acute fatty liver of pregnancy, a disorder limited to the gravid state, occurs in the third trimester of pregnancy and causes acute hepatic failure .
- The disorder is usually seen after the 35th week of gestation and is more common in primigravida and those with twins.
Management
- Diagnosis of acute fatty liver of pregnancy mandates immediate delivery.
- essential Intensive supportive care with ICU level observation is and typically includes administration of blood products and glucose as well as correction of acidemia.
- Vaginal delivery is preferred.
- Resolution of encephalopathy and laboratory derangements occur over days with supportive care and recovery is usually complete.