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Gynecologic and Obstetric Disorders

Typhoid Fever in Pregnancy

Not yet clinically reviewed

This protocol was migrated from the earlier Pharmapedia and Ward Guide apps for educational use. Follow your hospital's own policies and consult seniors when in doubt.

Typhoid fever can cause major complications to both for the mother (gastrointestinal perforation, peritonitis, and septicemia) and the fetus (Spontaneous abortion, Preterm birth, Intrauterine death).

  • Admit to inpatient department
  • In the absence od drug resistance, go for
  • Cap Amoxil (Amoxicillin) 1g, 1cap PO TDS for 14days.
  • In cases of drug resistance or severe infection, go for
  • Inj Ceftriaxone (Rocephin) 2-4g IV OD For 10 or 14 days in divided doses.
  • Supportive care for other complaints.
  • Fever persists 4 to 5 days after starting treatment, even when treatment is effective. It is essential to treat the fever and to monitor for maternal and foetal complications.