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Hematologic Disorders

Hemophilia

Not yet clinically reviewed

This protocol was migrated from the earlier Pharmapedia and Ward Guide apps for educational use. Follow your hospital's own policies and consult seniors when in doubt.

It is hereditary disease mainly affecting males but transmitted by females and characterized by prolong coagulation and a life long tendency to excessive hemorrhage

Types of Hemophilia

Hemophilia A: When factor VIII is deficientHemophilia B: When factor IX is deficient

symptoms

  • Internal bleeding of mouth, gums, lips, brain and kidney
  • Muscle hematoma
  • Joints become hot, swollen and very painful

Treatment

Blood tests to determine if clotting factors are missing or at low levels, and which ones are causing the problem.

Treatment

  • Factor VIII concentrate by infusion (Hemophilia A)
  • Factor XI infusion (Hemphilia B)