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Clinical Toxicology

Syndromes: Anticholinergic

Signs and symptoms

Tachycardia, hyperthermia, mydriasis, warm and dry skin, urinary retention, delirium (“mad as a hatter, blind as a bat, red as a beet, hot as a hare, and dry as a bone”*)

Common causes

Antihistamines

Atropine

Belladonna alkaloids

Jimson weed

Mushrooms (some)

Psychoactive drugs (many)

Scopolamine

Tricyclic antidepressants

Disclaimer: This guide is an educational reference for healthcare professionals. It does not replace clinical judgement — always follow your hospital's protocols and current guidelines.