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Clinical Toxicology

Syndromes: Anticholinergic

Not yet clinically reviewed

This protocol was migrated from the earlier Pharmapedia and Ward Guide apps for educational use. Follow your hospital's own policies and consult seniors when in doubt.

Signs and symptoms

Tachycardia, hyperthermia, mydriasis, warm and dry skin, urinary retention, delirium (“mad as a hatter, blind as a bat, red as a beet, hot as a hare, and dry as a bone”*)

Common causes

Antihistamines

Atropine

Belladonna alkaloids

Jimson weed

Mushrooms (some)

Psychoactive drugs (many)

Scopolamine

Tricyclic antidepressants